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Enzyme Information



This food grade fungal enzyme system used in National Enzyme Company products is obtained by the controlled fermentation of Trichoderma longibrachiatum (Trichoderma reesei). This enzyme system is a unique composition that aglyconates plant polyphenols, including isoflavones, through hydrolysis of their ß-Dglucopyranosidic linkage.


National Enzyme Company has developed and validated an internal method of analysis for this enzyme preparation. The resulting activity unit of Isolase® is described as “IsoU.” One “IsoU” is defined as the amount of enzyme that releases 1 μmole of p-Nitrophenol from p-Nitrophenyl-β-D Glucopyranoside in 1 minute, at 30° C and pH 7.5.


Isolase® is a unique enzyme composition used solely for the purpose of enhancing the bioavailability of plant polyphenols, including isoflavones. Isolase® is designed for addition to powdered drink mixes and encapsulated products that contain plant polyphenols. Additionally, Isolase® can be part of a digestive blend formulated to support the unique needs of individuals that consume diets high in soy or other sources of plant polyphenols.

Shelf Life:

Long term stability studies have not been completed for this composition. Based on shelf life studies of other carbohydrolytic preparations, this product has an expected shelf life of 24 months.

Typical Side Activities:

Cellulase, pentosanase, pectinase, alpha-glucosidase, and amylase


  • Form: Dry powder
  • Color: Light tan
  • Odor: Free of offensive odor
  • Taste: Free of offensive taste
  • Effective pH Range: pH 3.0 to 8.0
  • Effective Temperature Range:25°C to 40°C

Nothing disclosed above is to be construed as a recommendation to use our product in violation of any patents. The information presented above is believed to be accurate. However, said information and products are offered without warranty or guarantee except as to the composition and purity stated herein since the ultimate conditions of use and variability of the materials treated are beyond our control.

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